基于微流控芯片的生物传感器发展现状与展望*

doi:10.16257/j.cnki.1681-1070.2022.0603

摘要/Abstract

摘要： 微流控芯片具有样品体积小、检测成本低、检测时间短等优点，与光学传感器、电化学传感器和微波传感器结合可以构建灵敏度高、可重复、便携的检测系统。对微流控芯片在生物传感器中的最新应用进行了综述，并介绍了各种生物传感器的特性和原理，通过生物传感器和微流控芯片集成实现了对复杂样本的快速和高灵敏度检测。对未来的发展方向进行了展望，并提出了新一代生物微流控传感器发展中存在的挑战和应对问题的策略。

关键词: 微流控芯片, 光学生物传感器, 电化学生物传感器, 微波生物传感器

Abstract: Microfluidic chips show the advantages of small sample size, low detection cost and short detection time. Combined with optical sensors, electrochemical sensors and microwave sensors, a highly sensitive, repeatable and portable detection system can be constructed. The latest applications of microfluidic chips in biosensors are reviewed, the characteristics and principles of various bio-sensors are introduced. Through the integration of biosensors and microfluidic chips, rapid and high sensitivity detection of complex biomarkers is realized. The future development trend is prospected, and the strategies to deal with the challenges and problems in the development of the new generation of biological microfluidic sensors are proposed.

Key words: microfluidicchip, opticalbiosensor, electrochemicalbiosensor, microwavebiosensor

中图分类号:

TP212.3

杨晓君;张梦琦;任萌娜;李元岳;姚钊. 基于微流控芯片的生物传感器发展现状与展望^*[J]. 电子与封装, 2022, 22(6): 060502 .

YANG Xiaojun, ZHANG Mengqi, REN Mengna,LI Yuanyue, YAO Zhao. Development and Prospect of Biosensors Based onMicrofluidic Chips[J]. Electronics & Packaging, 2022, 22(6): 060502 .

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中国半导体行业协会封装分会会刊

中国电子学会电子制造与封装技术分会会刊

基于微流控芯片的生物传感器发展现状与展望^*

Development and Prospect of Biosensors Based onMicrofluidic Chips

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